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Table 3 Oocyst number of P. gallinaceum in Aedes and P. berghei in Anopheles. Mosquitoes were allowed to blood feed on the infected vertebrate hosts before and after treatment with primaquine derivatives (4b to 4p) or primaquine (15 mg/kg)

From: Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms

Compound tested (50 mg/kg) % Aedes infected (% reduction) % Anopheles infected (% reduction)
4b 80 (11%) 0 (100%)
4c 10 (89%) 0 (100%)
4d 80 (6%) 86 (4%)
4e 89 (0%) NT
4f 95 (5%) NT
4g 45 (50%) 0 (100%)
4h 90 (0%) 86 (0%)
4i 70 (13%) NT
4j 75 (0%) NT
4k 95 (5%) NT
4l 84 (16%) NT
4m 45 (55%) 0 (100%)
4n 95 (0%) 71 (30%)
4o 15 (85%) 0 (100%)
4p 75 (6%) 86 (0%)
Primaquine 0 (100%) 0 (100%)
  1. The % reduction of sporogony was calculated in relation to the control mosquitoes blood fed on the same animal host immediately before treatment