Skip to main content

Table 5 Characteristics of severe congenital malaria

From: A systematic review of the clinical presentation, treatment and relapse characteristics of human Plasmodium ovale malaria

Authors, year of publication

Sex

Birth weight (kg)

Previous residence of mother

Country of birth

Diagnostics

Parasitaemia

Body temperature (°C)

Hemoglobin level (g/dl)

Treatment

Outcome

Concomitant medication

Comment

Penazzato et al. [26], 2007

–

3.13

Nigeria

Italy

MIC + PCR

0.01%

–

5.4

Quinine sulphate 20 mg/kg/d for 5 days

Recovered without sequelae

Zidovudine

Mother HIV positive, no materno-foetal transmission of HIV

Jenkins et al. [27], 1957

M

4

East Africa

England

MIC

–

40

6.8

Proguanil 0.25 g daily for 5 days followed by: chloroquine sulphate ¼ tablet twice daily for 2 days, then ¼ tablet daily for 2 days, then ¼ tablet weekly for 3 weeks

Recovered without sequelae

Penicillin, potassium permanganate baths, local aqueous gentian violet 0.66%

Pubic rash after day 3

Erythromycin

Given on suspicion with proguanil

Ferrous sulphate

  1. MIC microscopy, PCR polymerase chain reaction, M male, – not mentioned in the original publication