Fig. 4

Relative immunogenicity of the NANP repeat and C-terminus regions of CSP. Data are expressed as the mean titre ratio (bars) ± SEM (whiskers) for mice (a, b; n = 7) and rhesus (c, d; n = 5) of NANP repeat titres (a, c) or C-terminus titres (b, d) to their respective FL antigen ELISA titre at post-first (P1), post-second (P2) and post-third (P3) vaccination with either CSP (solid bars) or Qβ-CSP (open bars). P values are shown for statistically significant differences between CSP and Qβ-CSP determined by two-tailed t tests