Fig. 2

Responses of naïve T lymphocytes to malaria parasites. HSCs-derived mononuclear cells (10 days old) were co-cultured with malaria antigens in various forms and uninfected erythrocyte controls. The bar graphs represent the fold changes of T lymphocytes sub-populations after 4 days of co-culture with the malaria antigens. CD3⁺4⁺8⁻ cells (a), CD3⁺4⁻8⁺ cells (b), CD3⁺4⁺8⁺ cells (c), and CD3⁺4⁻8⁻ cells (d) with standard deviations. The data are mean values obtained from five individual cord blood samples. *P ≤ 0.05, ***P ≤ 0.001, int.PfIEs intact P. falciparum-infected erythrocytes, int.PvIEs intact P. vivax-infected erythrocytes, int.UIEs intact uninfected erythrocytes, lys.PfIEs cell lysate from P. falciparum-infected erythrocytes, lys.PvIEs cell lysate from P. vivax-infected erythrocytes, lys.UIEs cell lysate from uninfected erythrocytes, PHA phytohemagglutinin