Fig. 5

Effects of malaria parasites on HLA-DR expression of antigen presenting cells. HSCs-derived mononuclear cells (10 days old) were co-cultured with malaria antigens in various forms and uninfected erythrocyte controls. The dark gray histograms represent the level of HLA-DR expression on the surface of the CD14⁺ cells, and CD40⁺ cells. The light gray histograms represent isotype controls after co-culture in the presence of the malaria parasite antigens for 4 days. Data are shown as mean fluorescence intensity (MFI) obtained from a selected cord blood representing the group