Skip to main content

Advertisement

Table 1 Efficacy estimates

From: A novel model fitted to multiple life stages of malaria for assessing efficacy of transmission-blocking interventions

Group   Arithmetic mean (±1.96 × SE) Median
  TBA TRA TBA TRA
Overall N bites (m) N cycles (i) 28.42 (28.0–28.9) 22.63 (21.7–23.6) 29.1 25.5
Per bite 1   28.42 (28.0–28.9) 22.63 (21.7–23.6) 29.1 25.5
2   70.77 (69.8–71.7) 91.18 (90.7–91.6) 75.0 93.9
3   58.60 (57.5–59.7) 88.58 (88.1–89.1) 62.5 91.2
4   28.37 (27.2–29.5) 34.53 (32.9–36.1) 30.8 40.9
5   5.87 (5.0–6.8) −4.72 (−6.5 to −3.0) 6.3 −4.0
Per cycle   1 4.80 (3.9–5.7) −8.78 (−10.6 to −7.0) 6.3 −12.2
  2 21.15 (20.3–22.0) 44.88 (43.8–45.9) 22.7 49.4
  3 30.20 (29.4–31.1) 28.63 (27.1–30.1) 31.3 35.0
  4 32.60 (31.7–33.5) 13.51 (11.7–15.3) 33.3 16.6
Per bite and cycle 1 1 28.42 (27.4–29.5) 4.16 (2.2–6.1) 28.6 1.3
1 2 34.5 (32.0–37.0) 67.30 (65.7–68.9) 50.0 78.0
1 3 75.53 (73.7–77.4) 94.33 (93.7–95.0) 100 100
1 4 97.60 (97.0–98.2) 99.56 (99.3–99.8) 100 100
2 1 99.70 (99.5–99.9) 99.9 (99.8–100) 100 100
2 2 16.14 (13.4–18.9) 60.97 (59.3–62.6) 33.3 71.8
2 3 55.14 (52.6–57.7) 90.18 (89.3–91.0) 66.7 96.9
2 4 88.9 (87.6–90.2) 98.07 (97.7–98.5) 100 100
3 1 97.93 (97.2–98.6) 99.74 (99.6–99.8) 100 100
3 2 25.95 (23.8–28.1) 41.85 (39.8–43.9) 33.3 53.1
3 3 31.60 (29.2–34.0) 44.80 (42.5–47.1) 33.3 57.5
3 4 34.4 (31.7–37.2) 47.7 (45.3–50.2) 50.0 61.6
4 1 38.60 (35.7–41.5) 49.7 (57.0–52.4) 50.0 66.3
4 2 10.65 (8.9–12.4) 33.6 (31.6–35.6) 20.0 44.0
4 3 8.88 (7.0–10.8) 15.18 (12.8–17.5) 0.0 22.1
4 4 8.29 (6.2–10.4) 7.87 (5.3–10.4) 0.0 14.2
5 1 3.23 (0.6–9.5) 4.00 (1.2–6.8) 0.0 9.5
5 2 10.15 (8.6–77.4) 34.9 (33.0–36.9) 20.0 44.1
5 3 8.65 (6.7–10.6) 14.98 (12.5–17.4) 0.0 21.8
5 4 4.12 (1.59–6.7) 5.99 (3.3–8.7) 0.0 11.2
  1. The mean and standard errors (±1.96 × SE) and median for prevalence, TBA and intensity efficacy, TRA estimates for biting rates 1–5 (the number of mosquito bites per mouse), transmission cycles 1–4, calculated from the posterior distributions of the probabilistic Bayesian model
  2. TBA transmission-blocking activity, TRA transmission-reducing activity