Skip to main content

Table 2 Prevalence of Pfmdr1 and Pfcrt point mutations in isolates from three health facilities in Hodh Elgharbi region in Mauritania

From: Characterization of Plasmodium falciparum genes associated with drug resistance in Hodh Elgharbi, a malaria hotspot near Malian–Mauritanian border

Gene

Codons

Aa

n (%)

Aioun

Kobeni

Tintane

Total

Pfcrt

K76T

K

12 (21)

42 (31)

33 (38)

87 (31)

K/T

8 (14)

15 (11)

10 (11)

33 (12)

T

36 (64)

80 (58)

44 (51)

160 (57)

Pfmdr1

N86Y

N

35 (70)

102 (77)

66 (80)

203 (77)

Y

15 (30)

30 (23)

16 (20)

61 (23)

Y184F

Y

14 (33)

46 (36)

20 (26)

80 (32)

F

29 (67)

81 (64)

57 (74)

167 (68)

S1034C

S

29 (100)

67 (96)

53 (98)

149 (97)

C

0

3 (4)

1 (2)

4 (3)

N1042D

N

29 (100)

76 (99)

49 (100)

154 (99)

D

0

1 (1)

0

1 (1)

D1246Y

D

37 (100)

81 (98)

70 (100)

188 (99)

Y

0

2 (2)

0

2 (1)

  1. aa amino acid, n number of isolates