Table 3 Diagnostic performance of PfHRP2-RDT compared with expert microscopy (gold standard) for detection of malaria in febrile children
Accuracy parameters | Value % (n/N) | Confidence intervals (95% CI) |
|---|---|---|
Diagnostic performance all year | ||
Sensitivity | 98.2 (334/340) | 96.2–99.3 |
Specificity | 58.9 (202/343) | 53.5–64.1 |
Positive predictive value | 70.3 (334/475) | 66–74.4 |
Negative predictive value | 97.1 (202/208) | 93.8–98.9 |
Diagnostic performance during dry season | ||
Sensitivity | 97.0 (97/100) | 91.5–99.4 |
Specificity | 65.6 (160/244) | 59.2–71.5 |
Positive predictive value | 53.6 (97/181) | 46–61 |
Negative predictive value | 98.2 (160/163) | 94.7–99.6 |
Diagnostic performance during rainy season | ||
Sensitivity | 98.8 (237/240) | 96.4–99.7 |
Specificity | 42.4 (42/99) | 32.5–52.8 |
Positive predictive value | 80.6 (237/294) | 75.6–85 |
Negative predictive value | 93.3 (42/45) | 81.7–98.6 |