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Table 1 Epidemiological and clinical analysis according to severity

From: Epidemiological and clinical assessment of a shared territorial malaria guideline in the 10 years of its implementation (Barcelona, North Metropolitan Area, Catalonia, Spain, 2007–2016)

  Total (%) Severe malaria (%) Uncomplicated malaria (%) p
Number of cases 190 (100) 34 (17.9%) 156 (82.1%)
Mean age (DE) 32 (13.8) 35.3 (11.1) 31.2 (14.3) NS
Sex
 Men 121 (63.7) 27 (79.4) 94 (60.3) 0.04
 Women 69 (36.3) 7 (20.6) 62 (39.7)  
Species
 P. falciparum 122 (64.2) 27 (79.4) 95 (60.9) NS
 P. vivax 44(23.2) 4 (11.8) 40 (25.6)  
 P. ovale 2 (1.1) 0 (0) 2 (1.3)  
 P. malariae 3 (1.6) 0 (0) 3 (1.9)  
 P. spp. 14 (7.4) 2 (5.9) 12 (7.7)  
 Co-infectionsa 5 (2.6) 1 (2.9) 4 (2.6)  
Positive Immunocromatography (N = 124) 109 (87.9) 27 (90) 82 (85.4) NS
Travel destination
 Sub-Saharan Africa 142 (74.7) 33 (97.1) 109 (69.9) 0.02
 Indian sub-continent 46 (24.2) 1 (2.9) 45 (28.8) 0.003
 Amèrica 2 (1.1) 0 (0) 2 (1.3)  
Length of trip ≤ 30 days (N = 147) 39 (26.5) 10 (29.4) 29 (18.5) NS
Presence of risk factorsb 8 (4.2) 0 (0) 8 (5.1%) NS
Immigrant 164 (86.3) 25 (73.5) 139 (89.1) 0.01
Travel reason
 Tourism 8 (4.2) 5 (14.7) 3 (1.9)  
 VFRs 171 (90) 25 (73.5) 146 (93.6) <0.001
 Business 11 (5.8) 4 (11.8) 7 (4.5)  
Prior travel advice 26 (13.7) 5 (14.7) 21 (13.4) NS
Chemoprophylaxis 19 (10) 4 (11.8) 15 (9.6) NS
Care level
 Primary care 64 (33.7) 2 (5.9) 62 (39.7) <0.001
 Emergency area 34 (17.9) 3 (8.8) 31 (19.9)  
 Medicine ward 87 (45.8) 24 (70.6) 63 (40.4) <0.001
 ICU 5 (2.6) 5 (14.7) 0 (0)  
Treatment
 Quinine 71 (37.4) 29 (85.3) 42 (26.9) <0.001
 Artemether 4 (2.1) 1 (2.9) 3 (1.9)  
 Atovaquone/Prog. 62 (32.6) 2 (5.9) 60 (38.5) <0.001
 Other 53 (27.9) 2 (5.9) 51 (32.7)  
Sequelae at discharge 3 (1.6) 3 (8.8) 0 (0) NS
Favourable clinical evolution (to 30 days) 190 (100) 34 (100) 156 (100)
Mortality 0 (0) 0 (0) 0 (0)
  1. a P. falciparum-P. malariae: 1, P. falciparum-P. ovale: 4
  2. bImmunodeficiency: 5, pregnancy: 2, age < 1: 1