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Table 3 Fully adjusted Cox regression models with follow-up period split at net distribution campaign

From: Proximity to vector breeding site and risk of Plasmodium vivax infection: a prospective cohort study in rural Ethiopia

  Period 1—week 1 to 48 (n = 7016) Period 2—week 49 to 101 (n = 6695)
RR (95% CI) P value RR (95% CI) P value
Increasing household proximity to breeding sitea 1.60 (1.29–1.98) < 0.001 1.46 (1.17–1.81) 0.001
Age at study entry
 ≥ 25 Ref   Ref  
 15–24 2.73 (0.88–8.47) 0.08 1.23 (0.50–3.00) 0.65
 5–14 9.87 (3.79–25.70) < 0.001 2.43 (1.15–5.13) 0.02
 0–4 10.79 (4.03–28.92) < 0.001 4.57 (2.13–9.79) < 0.001
Gender
 Males Ref   Ref  
 Females 0.79 (0.49–1.27) 0.33 0.96 (0.60–1.53) 0.85
Persons living in household
 ≤ 7 Ref   Ref  
 ≥ 8 0.83 (0.52–1.35) 0.46 1.81 (1.11–2.97) 0.02
ITN use fraction (%)b
 > 50 Ref   Ref  
 ≤ 50 0.67 (0.37–1.20) 0.18 1.68 (1.01–2.79) 0.04
  1. aDistance to breeding site categorized into: > 2700 m (ref); 2400–2700; 2100–2400; and < 2100 m, and modelled linearly
  2. bITN use was recorded weekly (starting from week 5) during the regular follow-up visits to households. Participants were asked if they slept under a ITN the night before the visit. Use fraction was calculated as the number of nights reportedly sleeping under a ITN divided by the total number of nights asked. During week 48, there was a net distribution campaign in the Kebele thus the follow-up period was split at this point. For those with P. vivax infection, ITN use fraction was calculated only for weeks prior to infection