| |
Period 1—week 1 to 48 (n = 7016)
|
Period 2—week 49 to 101 (n = 6695)
|
|---|
|
RR (95% CI)
|
P value
|
RR (95% CI)
|
P value
|
|---|
|
Increasing household proximity to breeding sitea
|
1.60 (1.29–1.98)
|
< 0.001
|
1.46 (1.17–1.81)
|
0.001
|
|
Age at study entry
|
|
≥ 25
|
Ref
| |
Ref
| |
|
15–24
|
2.73 (0.88–8.47)
|
0.08
|
1.23 (0.50–3.00)
|
0.65
|
|
5–14
|
9.87 (3.79–25.70)
|
< 0.001
|
2.43 (1.15–5.13)
|
0.02
|
|
0–4
|
10.79 (4.03–28.92)
|
< 0.001
|
4.57 (2.13–9.79)
|
< 0.001
|
|
Gender
|
|
Males
|
Ref
| |
Ref
| |
|
Females
|
0.79 (0.49–1.27)
|
0.33
|
0.96 (0.60–1.53)
|
0.85
|
|
Persons living in household
|
|
≤ 7
|
Ref
| |
Ref
| |
|
≥ 8
|
0.83 (0.52–1.35)
|
0.46
|
1.81 (1.11–2.97)
|
0.02
|
|
ITN use fraction (%)b
|
|
> 50
|
Ref
| |
Ref
| |
|
≤ 50
|
0.67 (0.37–1.20)
|
0.18
|
1.68 (1.01–2.79)
|
0.04
|
-
aDistance to breeding site categorized into: > 2700 m (ref); 2400–2700; 2100–2400; and < 2100 m, and modelled linearly
-
bITN use was recorded weekly (starting from week 5) during the regular follow-up visits to households. Participants were asked if they slept under a ITN the night before the visit. Use fraction was calculated as the number of nights reportedly sleeping under a ITN divided by the total number of nights asked. During week 48, there was a net distribution campaign in the Kebele thus the follow-up period was split at this point. For those with P. vivax infection, ITN use fraction was calculated only for weeks prior to infection
