Skip to main content

Table 3 Diagnostic test performance of nPCR-saliva and thick film microscopy with nPCR-blood as reference standard in the diagnosis of malaria

From: Detection of Plasmodium falciparum DNA in saliva samples stored at room temperature: potential for a non-invasive saliva-based diagnostic test for malaria

Test characteristic NPCR-saliva Thick film microscopy
Sensitivity [95%CI] 82% [72 to 90] 68% [56 to 78]
Specificity [95%CI] 99% [95 to 100] 100% [97 to 100]
PPV [95%CI] 97% [89 to 99] 100% [93 to 100]
NPV [95%CI] 91% [85 to 95] 85% [79 to 90]
PLR [95%CI] 59% [15 to 235]  
NLR [95%CI] 0.2 [0.11 to 0.29] 0.32 [0.23 to 0.44]
Observed agreements 93% 89%
Kappa value 0.8 0.7
  1. PPV, positive predictive values; NPP, negative predictive values; PLR, positive likelihood ratio; NLR, negative likelihood ratio