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Table 3 Diagnostic test performance of nPCR-saliva and thick film microscopy with nPCR-blood as reference standard in the diagnosis of malaria

From: Detection of Plasmodium falciparum DNA in saliva samples stored at room temperature: potential for a non-invasive saliva-based diagnostic test for malaria

Test characteristic

NPCR-saliva

Thick film microscopy

Sensitivity [95%CI]

82% [72 to 90]

68% [56 to 78]

Specificity [95%CI]

99% [95 to 100]

100% [97 to 100]

PPV [95%CI]

97% [89 to 99]

100% [93 to 100]

NPV [95%CI]

91% [85 to 95]

85% [79 to 90]

PLR [95%CI]

59% [15 to 235]

 

NLR [95%CI]

0.2 [0.11 to 0.29]

0.32 [0.23 to 0.44]

Observed agreements

93%

89%

Kappa value

0.8

0.7

  1. PPV, positive predictive values; NPP, negative predictive values; PLR, positive likelihood ratio; NLR, negative likelihood ratio
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Malaria Journal

ISSN: 1475-2875

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