Screening a protein kinase inhibitor library against Plasmodium falciparum

Malaria Journal

Table 1 Percentage inhibition of the growth of Plasmodium falciparum of known anti-malarials in the Prestwick Library

Name	Screening conc. (mM)	Percentage inhibition
Chloroquine diphosphate	0.004	104 ± 1
Pyrimethamine	0.008	101 ± 2
Artemisinin	0.007	100
Primaquine diphosphate	0.004	100 ± 4
Hydroquinine hydrobromide hydrate	0.005	99 ± 2
Atovaquone	0.005	99 ± 2
Mefloquine hydrochloride	0.005	97.4 ± 0.4
Proguanil hydrochloride	0.007	49 ± 4

ISSN: 1475-2875