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Table 3 The distribution of the proportion of IgG responders stratified according to study site

From: Variation in the immune responses against Plasmodium falciparum merozoite surface protein-1 and apical membrane antigen-1 in children residing in the different epidemiological strata of malaria in Cameroon

Recombinant antigen

Responders

Study site

Total n (%)

Univariate analysis

Multivariate analysis

Bamenda n (%)

Limbe n (%)

Yaounde n (%)

Maroua n (%)

Ngaoundere n (%)

χ²

p value

χ²

p value

AMA-1

Positive

53 (39.9)

79 (56.4)

68 (53.5)

27 (35.5)

23 (18.3)

242 (40.2)

49.741

< 0.0001

  

Negative

80 (60.1)

61 (43.6)

59 (46.5)

49 (64.5)

103 (81.7)

360 (59.8)

Total

133

140

127

76

126

602

MSP-1

Positive

72 (54.1)

104 (74.3)

91 (71.7)

36 (47.4)

49 (38.9)

352 (58.5)

48.294

< 0.0001

  

Negative

61 (45.9)

36 (25.7)

36 (28.3)

40 (52.6)

77 (61.1)

250 (41.5)

Total

133

140

127

76

126

602

Overall

Positive

89 (66.9)

128 (91.4)

107 (84.3)

43 (56.6)

67 (53.2)

434 (72.1)

68.626

< 0.0001

67.840a

< 0.0001

Negative

44 (33.1)

12 (8.6)

20 (15.7)

33 (43.4)

59 (46.8)

168 (27.9)

Total

133

140

127

76

126

602

  1. aChi square values obtained from the likelihood ratio tests adjusted for age and gender