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Table 4 The distribution of the proportion of responders stratified according to age

From: Variation in the immune responses against Plasmodium falciparum merozoite surface protein-1 and apical membrane antigen-1 in children residing in the different epidemiological strata of malaria in Cameroon

Recombinant antigen

Responders

Age category (years)

Total n (%)

Univariate analysis

Multivariate analysis

< 5 n (%)

5–9 n (%)

≥ 10 n (%)

χ2

p value

χ2

p value

AMA-1

Positive

85 (29.1)

94 (46.1)

63 (59.4)

242 (50.5)

34.185

< 0.0001

  

Negative

207 (70.9)

110 (53.9)

43 (40.6)

360 (49.5)

Total

292

204

106

602

MSP-1

Positive

160 (54.8)

117 (57.4)

75 (70.8)

352 (58.5)

8.317

0.016

  

Negative

132 (45.2)

87 (42.6)

31 (29.2)

250 (41.5)

Total

292

204

106

602

Overall

Positive

194 (66.4)

153 (75.0)

87 (82.1)

434 (72.1)

10.748

0.005

7.567a

0.009

Negative

98 (33.6)

51 (25.0)

19 (17.9)

168 (27.9)

Total

292

204

106

602

  1. aChi square values obtained from the likelihood ratio tests adjusted for gender and study site