Table 4 Comparison of demographics and baseline characteristics between groups of patients in intensive care need and death outcome
From: Are respiratory complications of Plasmodium vivax malaria an underestimated problem?
Variable | Intensive care unit | Final outcome | ||||
|---|---|---|---|---|---|---|
No (n = 18) | Yes (n = 12) | p-value | Discharged alive (n = 25) | Death (n = 5) | p-value | |
Age in years (mean ± SE) | 30.4 (± 4.3) | 45 (± 6.4) | 0.060 | 32.8 (± 4) | 53.6 (± 7.7) | 0.042 |
Sex (m/f) | 10/8 | 7/5 | 0.880 | 13/12 | 4/1 | 0.249 |
Comorbidities and concomitant conds. (n/%) | 6 (33.3) | 11 (91.6) | 0.002 | 12 (48) | 5 (100) | 0.032 |
Resp. symptoms at hospital admission (n/%) | 13 (72.2) | 10 (83.3) | 0.481 | 18 (72) | 5 (100) | 0.177 |
Time of previous symptoms (days—mean ± SE) | 5.4 (± 0.7) | 6.2 (± 1.1) | 0.501 | 5.6 (± 0.7) | 6.2 (± 1.3) | 0.740 |
Fever on admission (n/%) | 8 (44.4) | 4 (33.3) | 0.543 | 10 (40) | 2 (50) | 0.315 |
First malaria episode (n/%)a | 4 (30.7) | 3 (27.2) | 0.851 | 5 (25) | 2 (50) | 0.231 |
Resp. complications after anti-malarials (n/%) | 13 (72.2) | 10 (83.3) | 0.481 | 18 (72) | 5 (100) | 0.177 |
Anti-malarial treatment before hospitalization (n/%) | 7 (38.9) | 8 (66.6) | 0.264 | 12 (48) | 3 (60) | 1 |
Patients requiring haemodialysis (n/%) | 1 (5.5) | 4 (33.3) | 0.046 | 2 (8) | 3 (60) | 0.004 |
Haemoglobin (g/dL) (mean ± SE) | 10.2 (± 0.4) | 8.5 (± 0.6) | 0.003 | 9.9 (± 0.4) | 7.7 (± 0.7) | 0.037 |
Leucocytes (× 103/mm3) median (IQR) | 6.1 (3.9–9.5) | 8.8 (6.1–17) | 0.082 | 6.5 (4.4–9.9) | 9.7 (5.7–32) | 0.388 |
Platelet count (× 103/mm3) median (IQR) | 40 (30–75) | 80 (39.5–96) | 0.211 | 45 (30–91) | 81 (79–81) | 0.231 |
Creatinine (mg/dL) median (IQR)b | 0.9 (0.7–1) | 1.8 (0.9–3) | 0.024 | 1 (0.7–1.2) | 2.3 (0.9–3) | 0.368 |
Urea (mg/dL) median (IQR)b | 28 (21–35) | 70 (36–1555) | 0.004 | 30 (22–44) | 88 (41–194) | 0.034 |
Bilirubin (mg/dL) median (IQR)c | 1.6 (0.5–3.5) | 3.5 (1–12) | 0.149 | 1.6 (0.7–3.5) | 19.8 (6.7–36) | 0.053 |
Lactate dehydrogenase (U/L) (mean ± SE)d | 785.8 (± 60) | 1093 (± 196) | 0.098 | 762 (± 72) | 1420 (± 194) | < 0.001 |
AST (U/L) median (IQR) | 51 (31–58) | 47 (31.5–84) | 0.964 | 50 (33–58) | 38 (28–74) | 0.930 |
ALT(U/L) median (IQR) | 41.5 (26–69) | 28 (23.5–31) | 0.111 | 38 (27–66) | 25 (22–31) | 0.221 |
GGT (U/L) median (IQR) | 84 (52–259) | 131 (71–142) | 0.791 | 124 (53–192) | 71 (61–140) | 0.906 |
Alkaline Phosphatase (U/L) (mean ± SE)e | 378 (± 54) | 400 (± 149) | 0.861 | 392 (± 60) | 315 (± 15) | 0.674 |