Fig. 6

Influence of insecticide effectiveness and exposure on time-to-resistance for mixtures and sequences. Exposure to the insecticides is increased from row 1 (a, b) to row 2 (c, d). The effectiveness of one insecticide is increased from column 1 (a, c) to column 2 (b, d). On the upper X axis ‘s’ and ‘m’ indicate where the 50% resistance threshold is reached for the sequence and the mixture. In the lower right of each panel the ratio of time-to-resistance for mixture/sequence is shown rounded to 1 decimal place to give an indication of the relative performance of mixtures and sequences. a All control inputs equal at 0.5: time-to-resistance is longer for sequential use, b Effectiveness of insecticide 1 increased from 0.5 to 0.8: time-to-resistance is longer for the mixture, c exposure increased to 0.8: time-to-resistance is longer for sequential use, d effectiveness of insecticide 1 and exposure increased to 0.8: time-to-resistance equal for mixture and sequence. Increasing effectiveness increases times-to-resistance for mixtures and improves their performance relative to sequences. Increasing exposure decreases times-to-resistance for mixtures and reduces their performance relative to sequences