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Table 6 Detailed association of RNASE3 +499G/C genotypes with malaria severity

From: Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population

Genotypes Malaria Groups Nominal p value for Statistical test
SM UM CTR UM vs CTR SM vs CTR SM vs UM SM vs CTR + UM
p OR 95 %CI p OR 95 %CI p OR 95 %CI p OR 95 %CI
GG genotype as reference
 GG 70 41 31 1 1 1 1
 GC 18 27 21 0.670 1.21 (0.49–2.08) 0.014 0.33 (0.14–1.02) 0.006 0.32 (0.14–1.82) 0.002 0.34 (0.17–0.98)
 CC 4 7 2 0.210 3.15 (0.53–4.02) 0.365 0.37 (0.05–1.01) 0.013 0.11 (0.02–0.99) 0.040 0.18 (0.04–1.01)
CC genotype as reference
 CC 1 1 1 1
 GC 0.305 0.38 (0.06–0.98) 0.921 0.89 (0.10–1.01) 0.246 2.86 (0.48–3.25) 0.480 1.82 (0.34–2.35)
  1. This table gives RNASE3 u + 499G/C association analysis between groups. Significant p values are in italic. RNASE3 +499 GC and 499 CC genotypes induced significant association with severity. Logistic regression analysis were performed using plink analysis software. All the values OR were obtained with 95% CI