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Table 2 Prevalence of msp-1 K1, MAD20, and RO33 allelic variants collected from Plasmodium falciparum isolates along Grande Comore Island in 2006–2007 and 2013–2016 periods

From: Temporal changes in genetic diversity of msp-1, msp-2, and msp-3 in Plasmodium falciparum isolates from Grande Comore Island after introduction of ACT

K1 allele Number of isolates (%)a MAD20 allele Number of isolates (%)a RO33 allele Number of isolates (%)a
2006–2007 2013–2016 2006–2007 2013–2016 2006–2007 2013–2016
(n = 40) (n = 44) (n = 20) (n = 12) (n = 42) (n = 54)
K1-1 2 (5.0) 0 (0)* MAD20-1 5 (25.0) 5 (41.6)** RO33-1 7 (21.2) 32 (59.3)**
K1-2 0 (0) 2 (4.5)* MAD20-2 1 (5.0) 2 (16.6)** RO33-2 2 (6.1) 3 (5.6)
K1-3 1 (2.5) 0 (0) MAD20-3 2 (10.0) 5 (41.6)** RO33-3 8 (24.2) 1 (1.9)**
K1-4 3 (7.5) 0 (0)** MAD20-4 3 (15.0) 0 (0)** RO33-4 2 (6.1) 1 (1.9)
K1-5 0 (0) 5 (11.4)** MAD20-5 2 (10.0) 0 (0)** RO33-5 4 (12.1) 1 (1.9)**
K1-6 3 (7.5) 2 (4.5) MAD20-6 2 (10.0) 0 (0)** RO33-6 2 (6.1) 0 (0)**
K1-7 5 (12.5) 5 (11.5) MAD20-7 1 (5.0) 0 (0)* RO33-7 0 (0) 3 (5.6)*
K1-8 0 (0) 3 (6.8)** MAD20-8 1 (5.0) 0 (0)* RO33-8 3 (9.1) 0 (0)**
K1-9 2 (5.0) 2 (4.5) MAD20-9 3 (15.0) 0 (0)** RO33-9 0 (0) 2 (3.7)
K1-10 3 (7.5) 0 (0)**     RO33-10 3 (9.1) 0 (0)**
K1-11 2 (5.0) 8 (18.2)**     RO33-11 0 (0) 8 (14.8)**
K1-12 2 (5.0) 2 (4.5)     RO33-12 2 (6.1) 3 (5.6)
K1-13 3 (7.5) 9 (20.5)**       
K1-14 0 (0) 2 (4.5)*       
K1-15 2 (5.0) 0 (0)*       
K1-16 1 (2.5) 0 (0)       
K1-17 3 (7.5) 0 (0)**       
K1-18 8 (20.0) 4 (9.1)*       
  1. aStatistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (* P < 0.05; ** P < 0.01) using Mann–Whitney U test