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Table 4 Prevalence of msp-3 K1 and 3D7 allelic variants collected from Plasmodium falciparum isolates along Grande Comore Island in 2006–2007 and 2013–2016 periods

From: Temporal changes in genetic diversity of msp-1, msp-2, and msp-3 in Plasmodium falciparum isolates from Grande Comore Island after introduction of ACT

Allelic variants Number of isolates (%)a
2006–2007 (n = 105) 2013–2016 (n = 99) Total (n = 204)
K1-1 4 (7.6) 9 (9.1) 13 (6.4)
K1-2 12 (11.4) 37 (37.4)** 49 (24.0)
K1-3 12 (11.4) 0 (0)** 12 (5.9)
K1-4 2 (1.9) 0 (0) 2 (1.0)
K1-5 16 (15.2) 0 (0)** 21 (10.3)
K1-6 12 (11.4) 0 (0)** 12 (5.9)
K1-7 3 (2.9) 0 (0) 3 (1.5)
K1-8 4 (3.8) 0 (0) 4 (2.0)
3D7-1 21 (20.0) 53 (53.5)** 69 (33.8)
3D7-2 12 (10.4) 0 (0)** 12 (5.9)
3D7-3 7 (3.8) 0 (0)** 7 (3.4)
  1. aStatistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (* P < 0.05; ** P < 0.01) using Mann–Whitney U test