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Table 4 Prevalence of msp-3 K1 and 3D7 allelic variants collected from Plasmodium falciparum isolates along Grande Comore Island in 2006–2007 and 2013–2016 periods

From: Temporal changes in genetic diversity of msp-1, msp-2, and msp-3 in Plasmodium falciparum isolates from Grande Comore Island after introduction of ACT

Allelic variants

Number of isolates (%)a

2006–2007 (n = 105)

2013–2016 (n = 99)

Total (n = 204)

K1-1

4 (7.6)

9 (9.1)

13 (6.4)

K1-2

12 (11.4)

37 (37.4)**

49 (24.0)

K1-3

12 (11.4)

0 (0)**

12 (5.9)

K1-4

2 (1.9)

0 (0)

2 (1.0)

K1-5

16 (15.2)

0 (0)**

21 (10.3)

K1-6

12 (11.4)

0 (0)**

12 (5.9)

K1-7

3 (2.9)

0 (0)

3 (1.5)

K1-8

4 (3.8)

0 (0)

4 (2.0)

3D7-1

21 (20.0)

53 (53.5)**

69 (33.8)

3D7-2

12 (10.4)

0 (0)**

12 (5.9)

3D7-3

7 (3.8)

0 (0)**

7 (3.4)

  1. aStatistically significant differences for comparison with isolates circulating in 2006–2007 from Grande Comore island (* P < 0.05; ** P < 0.01) using Mann–Whitney U test