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Table 2 A comparison of the diagnostic tools RDT, microscopy and PCR; and test of their accuracy

From: Plasmodium falciparum diagnostic tools in HIV-positive under-5-year-olds in two ART clinics in Ghana: are there missed infections?

 

RDT/PCR

Microscopy/PCR

RDT/microscopy

Neg

352/339

345/339

352/345

Pos

49/62

56/62

49/56

p value*

< 0.05

< 0.05

< 0.05

  

Kappa co-efficient

0.83

RDT

Under 5 years (n = 150)

Under 5 years (n = 251)

 

HIV positive (95% CI)

HIV negative (95% CI)

Sensitivity

83 (53.5–100)

78.6 (67.8–89.3)

 

Specificity

100 (98.9–100)

100 (99.1–100)

 

Positive predictive value

100 (97.8–100)

100 (99.3–100)

 

Negative predictive value

99 (98–100)

94.2 (91–97.4)

 

Microscopy

Under 5 years (n = 150)

Under 5 years (n = 251)

 

HIV positive (95% CI)

HIV negative (95% CI)

Sensitivity (CI)

100 (99–100)

89.3 (81.2–97.4)

 

Specificity (CI)

100 (98.5–100)

100 (99.3–100)

 

Positive predictive value

100 (99.2–100)

100 (99–100)

 

Negative predictive value

100 (99.6–100)

97 (94.7–99.4)

 
  1. * p value using McNemar’s test