Investigating insecticide resistance and knock-down resistance (kdr) mutation in Dielmo, Senegal, an area under long lasting insecticidal-treated nets universal coverage for 10 years

Table 2 Association of kdr alleles with pyrethroid and DDT resistance phenotype in Anopheles arabiensis in Dielmo

Insecticides (N)	State	Genotype counts						Allelic association (additive model)
		LL	LF	FF	LS	SS	FS	Fisher exact test (p)		Odds ratio (95% CI)
		LL	LF	FF	LS	SS	FS	L vs F	L vs S	L vs F	L vs S
Pyrethroids (140)	Alive	11	0	2	6	4	2	(0.787)	(0.463)	1.17 (0.36–3.88)	1.38 (0.58–3.30)
Pyrethroids (140)	Dead	64	2	3	8	27	11	(0.787)	(0.463)	1.17 (0.36–3.88)	1.38 (0.58–3.30)
DDT (61)	Alive	20	0	2	6	10	2	(0.953)	(0.873)	1.06 (0.18–6.30)	1.09 (0.38–3.17)
DDT (61)	Dead	10	1	1	3	6	0	(0.953)	(0.873)	1.06 (0.18–6.30)	1.09 (0.38–3.17)

LL homozygous susceptible, LF heterozygous resistant for kdr-w, LS heterozygous resistant for kdr-e, FF homozygous resistant for kdr-w, SS homozygous resistant for kdr-e, FS heterozygous resistant for both kdr-w and kdr-e, L leucine, F phenylalanine, S serine

ISSN: 1475-2875