A systematic and prospectively validated approach for identifying synergistic drug combinations against malaria

Malaria Journal

Table 3 Gamma synergy values for ACT as current synergistic therapies

Compound 1	Compound 2	3D7 Gamma	DD2 Gamma	HB3 Gamma
Mefloquine	Artesunate	0.911**	0.786**	0.797**
Amodiaquine	Artesunate	0.993	1.064	0.955*
Sulfadoxine	Artesunate	0.986	1.016	0.936**
Lumefantrine	Artemether	2.221	1.058	0.997
Piperaquine	Dihydroartemisinin (DHA)	0.999	1.007	0.999

This table shows synergy metric gamma for current anti-malarial combination therapies for comparison reason to the results provided in Table 2 (similar markings)

ISSN: 1475-2875