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Table 3 Factors associated with newborn weight, maternal haemoglobin levels and incidence of malaria during the 1st year of life

From: IgM and IgG against Plasmodium falciparum lysate as surrogates of malaria exposure and protection during pregnancy

 

Newborn weight (kg)

Haemoglobin (g/L)

Incidence malaria children

Mean

95% CI

p

Mean

95% CI

p

IRR

95% CI

pb

Parity

 PG

2.8

2.69–2.91

< 0.001

113.1

105.4–120.7

0.878

1

  

 SG

2.9

2.81–2.99

 

113.3

107.9–119.6

 

1.64

0.61–4.43

0.331

 MG

3.13

3.05–3.20

 

111.5

107.2–115.8

 

1.07

0.44–2.59

0.878

Placental infection

 Negative

3.02

2.95–3.08

0.044

113

109.4–116.6

0.473

1

  

 Positive

2.89

2.77–2.99

 

110.1

102.1–118.1

 

0.95

0.39–2.27

0.915

Peripheral infection

 Negative

2.99

2.92–3.05

0.990

113.3

109.6–116.9

0.288

1

  

 Positive

2.99

2.89–3.08

 

108.9

101.1–116.7

 

1.82

0.79–4.18

0.161

Inflammation

 Negative

2.98

2.92–3.03

0.106

112.6

109.3–116.0

0.488

1

  

 Positive

3.19

2.92–3.46

 

107.0

90.26–123.7

 

2.96

0.72–12.02

0.130

Cord infection

 Negative

2.98

2.92–3.03

0.131

112.6

109.3–115.9

0.474

1

  

 Positive

3.2

2.72–3.68

 

106.4

88.9–123.9

 

5.90

1.53–22.77

0.010a

Age (years)

 15–20

2.78

2.69–2.87

< 0.001a

110.7

104.7–116.8

0.344

1

  

 21–24

3.03

2.95–3.12

 

116.2

110.0–122.3

 

0.79

0.31–1.98

0.608

 ≥ 25

3.14

3.05–3.23

 

110.9

105.7–116.0

 

0.88

0.38–2.05

0.769

Neighbourhood (km)

 > 2.5

3.00

2.94–3.06

0.328

111.1

114.7–107.5

0.122

1

  

 < 2.5

2.93

2.79–3.07

 

117.6

109.9–125.2

 

1.04

0.42–2.57

0.936

Use of ITN

 Negative

2.97

2.91–3.03

0.171

112.8

109.2–116.5

0.469

1

  

 Positive

3.09

2.92–3.28

 

109.1

102.4–115.9

 

1.07

0.34–3.35

0.903

Use of IRS

 Negative

2.94

2.87–3.02

0.109

113.3

108.5–118.1

0.573

1

  

 Positive

3.04

2.95–3.12

 

111.4

106.8–115.9

 

0.66

0.32–1.37

0.268

Season

 Rainy

2.98

2.91–3.05

0.685

110.2

106.2–114.3

0.049a

1

  

 Dry

3.01

2.89–3.11

 

117.4

111.8–123.0

 

0.99

0.44–2.21

0.980

  1. PG primigravida, SG secundigravida, MG multigravida, ITN insecticide-treated nets, IRS indoor residual spraying, IRR incidence rate ratio
  2. ap < 0.05 in the multivariate analysis adjusted by age, use of IRS and ITS, season and neighbourhood
  3. badjusted for treatment, weight and maternal haemoglobin