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Table 4 Haplotypes of Plasmodium falciparum isolates collected before 2009 and from 2009 to 2016

From: Phenotypic and genotypic characterization of Thai isolates of Plasmodium falciparum after an artemisinin resistance containment project

Group

Haplotype

Total

Before 2009

2009–2016

Pfmdr1

K13

n (%)

n (%)

n (%)

N86Y

Y184F

S1034C

N1042D

C580Y

R539T

100 (100.0)

49 (49.0)

51 (51.0)

I

86Y

Y184

S1034

N1042

C580

R539

7 (7.0)

7 (14.3)

0 (0)

II

N86

184F

S1034

N1042

C580

R539

26 (26.0)

20 (40.8)

6 (11.8)

III

N86

184F

S1034

N1042

580Y

R539

34 (34.0)

5 (10.2)

29 (56.9)

IV

N86

184F

S1034

N1042

C580

539T

8 (8.0)

1 (2.0)

7 (13.4)

V

N86

184F

S1034

1042D

C580

R539

5 (5.0)

4 (8.2)

1 (2.0)

VI

N86

184F

1034C

1042D

C580

R539

9 (9.0)

9 (18.4)

0 (0)

VII

Others

12 (12.0)

3 (6.1)

8 (15.7)

  1. Significant differences of haplotypes between parasites collected before 2009 and from 2009 to 2016 determined using Chi square test, p < 0.001