Table 3 Estimates female gametocyte carriage, circulation time and area under the curve (AUC)
Pyronaridine–artesunate | Artemether–lumefantrine | P-value | |
|---|---|---|---|
Pfs25 QT-NASBA | |||
Duration of gametocyte carriage (days), mean (95% CI) | 4.92 (4.10–5.73) | 3.77 (3.08–4.47) | 0.036 |
Circulation time (days), mean (95% CI) | 1.34 (1.12–1.56) | 0.96 (0.81–1.12) | 0.003 |
AUC (g/µl−1 day), median (IQR) | 0.52 (0.105–2.771) | 0.79 (0.177–3.150) | 0.617* |
Pfs25 qRT-PCR | |||
Duration of gametocyte carriage (days), mean (95% CI) | 4.46 (3.72–5.20) | 3.74 (3.04–4.44) | 0.166 |
Circulation time (days), mean (95% CI) | 1.38 (1.18–1.58) | 1.04 (0.89–1.20) | 0.004 |