Table 1 Hit compounds from the first screening using P. falciparum 3D7 strain
Compound | Growth inhibition rate (%) IC50 (SEM) (nM) |
|---|---|
Palmatine chloride | 99.5 26 (24–28) |
Berberine chloride | 99.7 36 (34–38) |
Coptisine chloride | 99.7 35 (34–36) |
Dehydrocorydaline nitrate | 99.7 38 (36–39) |
Timosaponin A-III | 99.7 Not determined due to its haemolytic effect |