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Table 1 Hit compounds from the first screening using P. falciparum 3D7 strain

From: Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts

Compound Growth inhibition rate (%) IC50 (SEM) (nM)
Palmatine chloride 99.5 26 (24–28)
Berberine chloride 99.7 36 (34–38)
Coptisine chloride 99.7 35 (34–36)
Dehydrocorydaline nitrate 99.7 38 (36–39)
Timosaponin A-III 99.7 Not determined due to its haemolytic effect