Table 2 Comparison of the main outcomes in women enrolled in IPTp-SP and ISTp-AL arms (at 36–40 weeks gestation and birth)
Outcome | ATP analysis | mITT analysis | ||||
|---|---|---|---|---|---|---|
Control (IPTp-SP) | Intervention (ISTp-AL) | p-value | Control (IPTp-SP) | Intervention (ISTp-AL) | p-value | |
Severe anaemia (Hb < 8 g/dl) | 2/114 (1.7) | 0/124 (0) | 0.133 | 2/115 (1.7) | 0/124 (0) | 0.142 |
Moderate anaemia (Hb 8–10.9 g/dl) | 36/114 (31.6) | 30/124 (24.2) | 36/115 (31.3) | 30/124 (24.2) | ||
Hb ≥ 11 g/dl | 76/114 (66.7) | 94/124 (75.8) | 77/115 (67) | 94/124 (75.8) | ||
Mean haemoglobin g/dl (SD) | 11.4 (1.3) | 11.7 (1.2) | 0.073 | 11.4 (1.4) | 11.7 (1.2) | 0.076 |
Birth weight | ||||||
Normal (≥ 2.5 kg) | 130/139 (93.5) | 139/147 (94.6) | 0.712 | 148/158 (93.7) | 157/167 (94) | 0.898 |
Low (< 2.5 kg) | 9/139 (6.5) | 8/147 (5.4) | 10/158 (6.3) | 10/167 (6.0) | ||
Mean (SD) | 3.21 (0.51) | 3.18 (0.54) | 0.062 | 3.21 (0.53) | 3.17 (0.53) | 0.497 |
Median (IQR) | 3.2 (0.6) | 3.2 (0.6) | 3.2 (0.6) | 3.2 (0.6) | ||
Parasitaemia | ||||||
Peripheral blood (light microscopy) All infections | 4/96 (4.2) | 2/112 (1.8) | 0.304 | 4/96 (4.2) | 2/112 (1.8) | 0.304 |