Fig. 3

The effects of varying the relative fitness of the mutant strain and the mutation rate in the mosquito population on the time to confirmed partial resistance (as measured by the time from mutant strain introduction until ≥ 5% of patients carry parasites with K13 mutation and a slow-clearing phenotype). The relationship between prevalence and time to resistance classification as the relative fitness of the mutant strain is varied in 5% relative increments (left), and as the mutation rate is varied among the mosquito population in 5% relative increments (right)