Skip to main content

Advertisement

Table 3 Multivariable logistic regression and bootstrap analysis for predictors for development of sepsis in patients admitted for severe malaria

From: Identifying risk factors for the development of sepsis during adult severe malaria

Predictors Category aOR 95% CI p value BOR B 95% CI B p value
Sex*,b Female 2.36 1.34, 4.17 0.003 2.36 1.30, 4.29 0.005
Male 1.00    1.00   
Coma on admissionb Yes 2.17 1.21, 3.90 0.010 2.17 1.19, 3.93 0.011
No 1.00    1.00   
Prostration on admission Yes 1.00 0.55, 1.84 0.989 1.00 0.55, 1.84 0.989
No 1.00    1.00   
Mean arterial pressure (mmHg)   0.99 0.97, 1.01 0.325 0.99 0.97, 1.01 0.308
Shock on admissionb Yes 2.85 1.35, 5.99 0.006 2.85 1.29, 6.28 0.009
No 1.00    1.00   
Haemoglobin on admission (mg/dl)   0.98 0.90, 1.07 0.646 0.98 0.89, 1.08 0.687
BUN (mg/dl)*,b   1.01 1.00, 1.02 0.004 1.01 1.00, 1.02 0.005
Visible jaundice on admissionb Yes 1.78 1.03, 3.07 0.038 1.78 1.02, 3.10 0.042
No 1.00    1.00   
Base excess on admission (mmol/l)   1.01 0.97, 1.05 0.735 1.01 0.97, 1.05 0.742
Anion gap on admission*,b   1.02 1.01, 1.05 0.043 1.02 1.00, 1.05 0.050
Percentage parasitaemia on admission (%)b   1.03 1.01, 1.06 0.008 1.03 1.01, 1.06 0.014
Respiratory rate on admission (cycles/minute)   0.98 0.95, 1.02 0.344 0.98 0.95, 1.02 0.328
Respiratory distress on admissionb Yes 3.62 1.69, 7.76 0.013 3.62 1.64, 8.02 0.002
No 1.00    1.00   
Somers’ Da   0.52    0.49   
  1. aOR adjusted odds ratio, CI confidence interval, BUN blood urea nitrogen, BOR bootstrapped odds ratio, B bootstrapped, mmol/l millimoles per litre, mg/dl milligrams per decilitre
  2. * Variables significant on multivariable analysis
  3. aEstimate of optimism = 0.03
  4. bIncluded in final regression model