Table 2 Mutations characterized in the different genes related to resistance to malaria drugs analyzed
From: Imported and autochthonous malaria in West Saudi Arabia: results from a reference hospital
Sample number | Nationality | DHPS genotype | DHFR genotype | CytB genotype | MDR genotype | CRT genotype | K13 genotype | |
|---|---|---|---|---|---|---|---|---|
N86Y | D1246Y | |||||||
1 | Nigerian | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
2 | Sudanese | S436A, K540E | N51I, C59R, S108N | Wild | Wild | Wild | M74I, N75E, K76T | Wild |
3 | Saudi | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
6 | Ethiopian | K540E | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
10 | Saudi | K540E | N51I, S108N | Wild | N86Y | Wild | Wild | Wild |
15 | Sudanese | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
16 | Sudanese | S436A | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
17 | Saudi | K540E, A581G | N51I, C59R, S108N | Wild | Wild | Wild | Wild | Wild |
18 | Sudanese | NA | NA | NA | NA | Wild | Wild | NA |
19 | Sudanese | S436A | N51I, C59R, S108N | Wild | Wild | Wild | M74I, N75E, K76T | Wild |
20 | Indian | S436A, K540E | N51I, S108N | Wild | N86Y | Wild | M74I, N75E, K76T | Wild |
21 | Sudanese | A437G | N51I, S108N | Wild | Wild | Wild | Wild | Wild |
26 | Saudi | – | N51I, C59R, S108N | Wild | N86Y | Wild | M74I, N75E, K76T | Wild |