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Table 4 Proportion of patients with no detectable parasites grouped by malaria species and treatment arm

From: Efficacy of artemether–lumefantrine and dihydroartemisinin–piperaquine for the treatment of uncomplicated malaria in Papua New Guinea

 

P. falciparum

P. vivax

AL

DHA-PPQ

P-value*

AL

DHA-PPQ

P-value*

A) Fever clearance**

 Day 1

88.2 (60/68)

100 (64/64)

0.008

92.9 (13/14)

90.1 (10/11)

1.00

 Day 2

95.6 (65/68)

98.4 (63/64)

0.62

92.9 (13/14)

90.1 (10/11)

1.00

 Day 3

100 (68/68)

96.9 (62/64)

0.24

100 (14/14)

90.1 (10/11)

0.46

 Day 7

100 (68/68)

98.4 (63/64)

0.49

100 (14/14)

90.1 (10/11)

0.46

B) Parasite clearance

 Day 1

64.3 (83/129)

70 (101/145)

0.7

92.9 (26/28)

90.5 (38/42)

1.00

 Day 2

96.1 (124/129)

100 (142/142)

0.93

100 (28/28)

100 (42/42)

1.00

 Day 3

99.2 (128/129)

100 (143/143)

1.00

100 (28/28)

100 (42/42)

1.00

 Day 7

100 (129/129)

99 (141/142)

1.00

100 (28/28)

100 (42/42)

1.00

  1. Values are presented as % (n/N)
  2. * Fisher’s exact test
  3. ** Fever clearance was defined as axillary temperature < 37.3 °C after two consecutive events with ≥ 37.3 °C starting from day 0