Diagnostic strategy | Sensitivity %, (95% CI) | Specificity %, (95% CI) | Predictive value | Likelihood ratio | Methods agreement %, (95% CI) | κ, (95% CI) | ||
---|---|---|---|---|---|---|---|---|
Positive test %, (95% CI) | Negative test %, (95% CI) | Positive test % | Negative test % | |||||
Drug seller interpretation of RDT strip (drug seller) | 81.7, (69.6, 90.5) | 90.6, (84.5, 94.9) | 79.0, (66.8, 88.3) | 92.0, (86.1, 95.9) | 8.7 | 0.2 | 87.9, (82.6, 92.1) | 0.72, (0.61, 0.82) |
Laboratory scientist re-reading of RDT strip (laboratory scientist) | 86.9, (75.8, 94.2) | 95.7, (90.8, 98.4) | 89.8, (79.2, 96.2) | 94.3, (89.1, 97.5) | 20.0 | 0.1 | 92.9, (88.5, 96.1) | 0.83, (0.75, 0.92) |
PCR analysis of P. falciparum DNA extracted from RDT nitrocellulose strip (RDT-PCR) | 76.6, (64.3, 86.2) | 95.9, (91.4, 98.5) | 89.1, (77.8, 95.9) | 90.4, (84.7, 94.6) | 18.9 | 0.2 | 90.1, (85.3, 93.8) | 0.76, (0.66, 0.85) |