Table 2 Demographic and clinical data

Age, years

 Median (IQR)

18 (11–31)

 Range

3–62

Children (age ≤ 12 years), n (% total)

14 (29)

Male gender, n (%)

38 (78)

Previous malaria (self-reported), n (%)

7 (14)

History of chronic disease, n (%)

0 (0)

Days of fever, median (IQR)

5 (3–6)

Symptoms on enrolment, n (%)

 Rigors/chills

33 (67)

 Headache

45 (92)

 Vomiting

24 (49)

 Abdominal pain

15 (31)

 Diarrhoea

6 (12)

 Cough

16 (33)

 Shortness of breath

5 (10)

 Myalgia

21 (43)

 Arthralgia

22 (45)

Examination findings on enrolment

 Temperature, °C, median (IQR)

37.3 (37.0–38.2)

 Fever, temp ≥ 37.5 °C, n (%)

20 (41)

 Systolic blood pressure, mmHg, median (IQR)

111 (99–120)

 Heart rate, beats/min, median (IQR)

96 (83–106)

 Respiratory rate, breaths/min, median (IQR)

22 (20–24)

 Oxygen saturation, %, median (IQR)

99 (98–100)

 Palpable liver, n (%)

11 (22)

 Palpable spleen, n (%)

5 (10)

 Rash, n (%)

Laboratory findings on enrolment

 Parasite count, parasites/μL, median (IQR)

9924 (3466–24,276)

 Parasite count, parasites/μL, range

1459–56,789

 Parasite count, parasites/μL, geometric mean (95% CI)

9463 (6757–13,254)

 Ring proportion, mean  % (SD)

89 (0.24)

 Haemoglobin, g/dL, median (IQR)

12.3 (11.0–13.9)

 Anemia (baseline), n (%)*

24 (49)

 G6PD deficiency present, n/N (%)

1/38 (97)

 White blood cell count, × 10³/μL, median (IQR)

6.9 (5.6–8.9)

 Neutrophil count, × 10³/μL, median (IQR)

4.1 (2.5–6.0)

 Platelet count, × 10³/μL, median (IQR)

122 (57–190)

 Thrombocytopenia (platelets < 150 × 10³/μL), n (%)

30 (61)

 Creatinine, μmol/L, median (IQR)

69 (50–82)

 Urea, mmol/L, median (IQR)

4.6 (3.3–5.8)

 Bilirubin, μmol/L, median (IQR)

14.6 (9.3–24.0)

 Glucose, mmol/L, median (IQR)

6.3 (5.5–7.1)

 Albumin, g/dL, median (IQR)

34 (28–37)

 ALT, IU/L, median (IQR)

30 (20–45)

 Bicarbonate, mmol/L, median (IQR)

20.9 (20.0–22.8)

 Acute kidney injury, n (%)

3 (6)

 Blood cultures positive, n (%)^✝

0/29 (0)