Prevalence of pfdhfr and pfdhps mutations in Plasmodium falciparum isolates from Kalimantan, Lombok and Papua patients in 2004–2006 and 2009–2012. The horizontal axis is the amino acid position or codon of mutations in pfdhfr and pfdhps genes. The white box indicates the wild-type and the texture boxes are mutants written by amino acid abbreviations. A = alanine, N = asparagine, R = arginine, I = isoleucine, L = leucine, S = serine, G = glycine, K = lysine, E = glutamic acid, T = threonine, F = phenylalanine, C = cysteine. Mixed genotype infections are presented as I/L or E/T et al.