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Table 4 Non-synonymous variants per person compared with the Cambridge Reference Sequence

From: Mitochondrial gene sequence variants in children with severe malaria anaemia with or without lactic acidosis: a case control study

  All subjects n = 73 High lactate n = 36 Normal lactate n = 37
Variants/person Variants/person/1000 nts Variants/person Variants/person/1000 nts Number of individuals Variants/person Variants/person/1000 nts Number of individuals
ND1 0.21 0.21 0.25 0.26 8 0.16 0.17 6
ND2 0.49 0.47 0.56 0.53 12 0.43 0.42 11
COI 0.60 0.39 0.61 0.40 17 0.59 0.39 13
COII 0.11 0.16 0.14 0.20 4 0.08 0.12 3
ATP8/6 2.44 2.90 2.42 2.87 36 2.46 2.92 37
COIII 0.15 0.19 0.17 0.21 6 0.14 0.17 6
ND3 1.23 3.56 1.33 3.85 36 1.14 3.28 24
ND4L/4 0.18 0.11 0.19 0.12 7 0.16 0.10 4
ND5 1.38 0.76 1.56 0.86 25 1.22 0.67 24
ND6 0.14 0.26 0.17 0.32 5 0.11 0.21 4
Cyto-b 2.96 2.59 2.97 2.60 36 2.95 2.58 37
Total 9.89 0.87 10.36 0.91 36 9.43 0.83 37
  1. The average number of non-synonymous variants per person and the average number of variants per person per 1000 nucleotides (nts) is shown. The number of individuals with at least one non-synonymous variant is shown