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Table 3 Comparison of the levels of the different IgG subclasses within the different study sites

From: Comparative analysis of IgG and IgG subclasses against Plasmodium falciparum MSP-119 in children from five contrasting bioecological zones of Cameroon

Bioecological strata Study site IgG1 IgG2 IgG3 IgG4 IgG subtype pattern p-value
HWP Bamenda 1.8017 ± 0.3213 1.1537 ± 0.3213 2.2087 ± 0.3238 1.1843 ± 0.3299 IgG3 > IgG1 > IgG4 > IgG2 0.017
SCEF Yaoundé 2.4315 ± 0.3722 1.4344 ± 0.3673 2.4139 ± 0.3769 1.3981 ± 0.437 IgG1 > IgG3 > IgG2 > IgG4 0.003
HIP Ngaoundere 1.0869 ± 0.3791 1.1013 ± 0.3487 1.0632 ± 0.3988 1.0096 ± 0.4467 IgG2 > IgG1 > IgG3 > IgG4 0.274
SS Maroua 1.1305 ± 0.3439 1.2379 ± 0.3532 1.1015 ± 0.3996 1.0139 ± 0.4510 IgG2 > IgG1 > IgG3 > IgG4 0.184
C Limbe 2.4534 ± 0.2970 1.4371 ± 0.2862 2.4409 ± 0.3176 1.4311 ± 0.3259 IgG1 > IgG3 > IgG2 > IgG4 0.011
  Overall 2.2754 ± 0.3751 1.2657 ± 0.3663 2.2617 ± 0.3922 1.2283 ± 0.4332 IgG3 > IgG1 > IgG2 > IgG4 0.027
  1. The figures represent mean antibody titres and their respective standard deviations. ANOVA was used to compare the mean antibody levels of the different IgG subclasses for each study site
  2. SCEF: South Cameroonian equatorial forest strata, SS: sudano-sahelian strata, HIP: high inland plateau strata, HWP: high western plateau strata, C: coastal strata