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Table 3 Comparison of the levels of the different IgG subclasses within the different study sites

From: Comparative analysis of IgG and IgG subclasses against Plasmodium falciparum MSP-119 in children from five contrasting bioecological zones of Cameroon

Bioecological strata

Study site

IgG1

IgG2

IgG3

IgG4

IgG subtype pattern

p-value

HWP

Bamenda

1.8017 ± 0.3213

1.1537 ± 0.3213

2.2087 ± 0.3238

1.1843 ± 0.3299

IgG3 > IgG1 > IgG4 > IgG2

0.017

SCEF

Yaoundé

2.4315 ± 0.3722

1.4344 ± 0.3673

2.4139 ± 0.3769

1.3981 ± 0.437

IgG1 > IgG3 > IgG2 > IgG4

0.003

HIP

Ngaoundere

1.0869 ± 0.3791

1.1013 ± 0.3487

1.0632 ± 0.3988

1.0096 ± 0.4467

IgG2 > IgG1 > IgG3 > IgG4

0.274

SS

Maroua

1.1305 ± 0.3439

1.2379 ± 0.3532

1.1015 ± 0.3996

1.0139 ± 0.4510

IgG2 > IgG1 > IgG3 > IgG4

0.184

C

Limbe

2.4534 ± 0.2970

1.4371 ± 0.2862

2.4409 ± 0.3176

1.4311 ± 0.3259

IgG1 > IgG3 > IgG2 > IgG4

0.011

 

Overall

2.2754 ± 0.3751

1.2657 ± 0.3663

2.2617 ± 0.3922

1.2283 ± 0.4332

IgG3 > IgG1 > IgG2 > IgG4

0.027

  1. The figures represent mean antibody titres and their respective standard deviations. ANOVA was used to compare the mean antibody levels of the different IgG subclasses for each study site
  2. SCEF: South Cameroonian equatorial forest strata, SS: sudano-sahelian strata, HIP: high inland plateau strata, HWP: high western plateau strata, C: coastal strata