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Fig. 6 | Malaria Journal

Fig. 6

From: In vivo compartmental kinetics of Plasmodium falciparum histidine-rich protein II in the blood of humans and in BALB/c mice infected with a transgenic Plasmodium berghei parasite expressing histidine-rich protein II

Fig. 6

Investigation of PfHRP2 persistence in once-infected RBCs post-treatment. a PbPfHRP2 iRBCs were isolated from mice pre-treatment and once-infected RBCs were isolated on days 2, 3, and 4 post-treatment with artesunate and pyronaridine. Uninfected mouse RBCs were used as a control. b P. falciparum iRBCs were collected from a patient pre-treatment. RBCs once-infected with P. falciparum were isolated from the same human patient on days 2, 3, and 12 post-treatment with artemether–lumefantrine. Uninfected human RBCs were used as a control. Once-infected RBCs were defined as cells with positive PfHRP2 staining (red) but no DAPI staining (blue)

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Malaria Journal

ISSN: 1475-2875

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