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Table 2 Sensitivity and specificity of MG-LAMP and microscopy using PET-PCR as a reference

From: Field evaluation of malaria malachite green loop-mediated isothermal amplification in health posts in Roraima state, Brazil

 

Method

Sensitivity

Specificity

Genusa

Microscopy

(n = 91)

83% (95% CI 67.22–92.66%)

100% (95% CI 93.02–100.00%)

MG-LAMP

(n = 91)

90% (95% CI 76.34–97.21%)

94% (95% CI 83.76–98.77%)

P. falciparum

Microscopy

(n = 91)

64% (95% CI 93.02–100.00%)

99% (95% CI 93.23–99.97%)

MG-LAMP

(n = 39)

82% (95% CI 48.22–97.72%)

100% (95% CI 95.49–100.00%)

P. vivax

Microscopy

(n = 91)

83% (95% CI 65.28–94.36%)

98% (95% CI 91.20–99.96%)

MG-LAMP

(n = 39)

90% (95% CI 73.47–97.89%)

100% (95% CI 94.13–100.00%)

  1. aSamples which were negative for genus were considered to be negative for species in the sensitivity and specificity calculations