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Table 4 Day 0 prevalence of different Pfmdr1 single nucleotide polymorphisms at the four sites covered in the therapeutic efficacy study in 2016

From: Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania

SNP

Kibaha

Mkuzi

Mlimba

Ujiji

Total

N86a

79 (98.8)

87 (98.9)

87 (98.9)

88 (100.0)

341 (99.1)

184F

34 (42.5)

41 (46.6)

30 (34.1)

32 (36.4)

137 (39.8)

D1246

80 (100.0)

87 (98.9)

87 (98.9)

88 (100.0)

342 (99.4)

  1. aOne sample from Mlimba had an N86I mutation while the others with mutations at this SNP possessed N86Y (2 samples, one each from Kibaha and Mkuzi)
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Malaria Journal

ISSN: 1475-2875

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