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Table 1 Baseline characteristics of children enrolled at Kibaha and Ujiji

From: High cure rates and tolerability of artesunate–amodiaquine and dihydroartemisinin–piperaquine for the treatment of uncomplicated falciparum malaria in Kibaha and Kigoma, Tanzania

Variable

Study sites

Overall

Kibaha

Ujiji

DP

ASAQ

DP

ASAQ

Screened

144

101

191

288

724

Enrolled

88 (61.1)

69 (68.3)

88 (46.1)

88 (30.6)

333 (46.0)

Age in years, mean (SD)

5.5 (2.8)

5.0 (2.7)

4.8 (2.6)

4.7 (2.8)

5.0 (2.7)

Gender (male), n (%)

54 (61.4)

34 (49.3)

45 (51.1)

53 (63.2)

186 (55.7)

Weight (kg), median (IQR)**

17 (13.3–21)

15 (12.5–22)

14 (12–18)

14.6 (11–18.5)

15 (12–19)

Height in cm, median (IQR)***

109 (93–123)

104 (92.5–121)

101 (83–112)

101 (86–115)

104 (90–119)

Body temp (°C) ± mean (SD)

37.9 (1.2)

37.8 (1.1)

38.2 (1.3)

38.0 (1.4)

38.0 (1.2)

Parasitaemia-GMPD (asexual pf/µl) 95% CI*

24,974 (18,822–33,136)

24,441 (16,166–36,954)

36,726 (27,481–49,082)

36,137 (28,809–45,329)

30,357 (26,157–35,231)

  1. °C, degree Celsius; SD, standard deviation; GMPD, Geometric mean parasite density; pf, Plasmodium falciparum; 95% CI, 95% confidence interval; n, number of patients; IQR, Inter quartile range; µl, microlitre; ETF, early treatment failure; LCF, late clinical failure; LPF, late parasitological failure; ACPR, adequate clinical and parasitological response; PP, number of patients involved in the per protocol analysis; LFU, lost to follow-up; WD, withdrawn; n, number of episodes
  2. * p = 0.013, ** p = 0.003, *** p < 0.001