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Table 6 Difference in the proportion of nets passing WHO 2005 threshold criteria by combined WHO cone and Tunnel test methods compared to I-ACT for sampled Olyset®, PermaNet® 2.0 and NetProtect® nets

From: Comparing the new Ifakara Ambient Chamber Test with WHO cone and tunnel tests for bioefficacy and non-inferiority testing of insecticide-treated nets

 

No. of nets tested

% pass WHO 2013 criteria (n)

% pass WHO 2005 criteria (n)

Odds ratio

95% confidence interval

p-value

Olyset®

 WHO methods

145

71% (n = 103)

77% (n = 111)

1

  

 I-ACT

145

94% (n = 134)

94% (n = 137)

5.2

2.3–11.8

< 0.0001

PermaNet® 2.0

 WHO methods

144

94% (n = 135)

94% (n = 135)

1

  

 I-ACT

144

98% (n = 141)

98% (n = 141)

3.1

0.8–11.8

0.092

NetProtect®

 WHO methods

143

99% (n = 141)

99% (n = 141)

1

  

 I-ACT

143

98% (n = 140)

97% (n = 139)

0.49

0.1–2.7

0.418

Overall

 WHO methods

432

69% (n = 379)

90% (n = 387)

1

  

 I-ACT

432

92% (n = 415)

97% (n = 417)

3.5

1.9–6.5

< 0.0001

  1. Odds ratios are calculated using pass/fail with 24 h holding times for all tests
  2. WHOPES 2005 pass/fail criteria: tunnel test: feeding inhibition and/or ≥ 80% 24 h mortality
  3. I-ACT: ≥ 80% 24 h mortality and/or ≥ 90% blood feeding inhibition