|
Placental pathology n/N (%)a
|
n
|
Term
|
Preterm
|
Relative risk (95% CI)
|
P
|
Adjusted relative risk (95% CI)
|
P
badj
|
|---|
|
Acute malaria
|
181
|
10/150 (6.7)
|
2/31 (6.5)
|
0.97 (0.26; 3.62)
|
0.97
|
0.99 (0.27; 3.66)
|
0.99
|
|
Chronic malaria
|
181
|
35/150 (23.3)
|
13/31 (41.9)
|
2.00 (1.06; 3.78)
|
0.039
|
1.49 (0.75; 2.94)
|
0.26
|
|
Past malaria
|
181
|
81/150 (54.0)
|
15/31 (48.4)
|
0.83 (0.44; 1.58)
|
0.57
|
1.08 (0.56; 2.08)
|
0.82
|
|
Chorioamnionitis grade 3
|
179
|
11/148 (7.4)
|
2/31 (6.5)
|
0.88 (0.23; 3.32)
|
0.85
|
1.00 (0.25; 4.00)
|
0.99
|
|
Chorioamnionitis grades 2 and 3
|
179
|
67/148 (45.3)
|
13/31 (41.9)
|
0.89 (0.46; 1.72)
|
0.73
|
0.96 (0.49; 1.87)
|
0.90
|
|
Placental pathology n/N (%)a
|
n
|
AGA
|
SGA
|
Relative risk (95% CI)
|
P
|
Adjusted relative risk (95% CI)
|
P
badj
|
|---|
|
Acute malaria
|
179
|
7/115 (6.1)
|
5/64 (7.8)
|
1.18 (0.58; 2.39)
|
0.66
|
1.03 (0.53; 1.99)
|
0.94
|
|
Chronic malaria
|
179
|
30/115 (26.1)
|
17/64 (26.6)
|
1.02 (0.65; 1.59)
|
0.95
|
0.80 (0.50; 1.27)
|
0.32
|
|
Past malaria
|
179
|
63/115 (54.8)
|
32/64 (50.0)
|
0.88 (0.60; 1.31)
|
0.54
|
1.06 (0.71; 1.57)
|
0.80
|
|
Chorioamnionitis grade 3
|
177
|
9/114 (7.9)
|
4/63 (6.3)
|
0.86 (0.37; 1.99)
|
0.70
|
1.02 (0.45; 2.27)
|
0.97
|
|
Chorioamnionitis grades 2 and 3
|
177
|
54/114 (47.4)
|
26/63 (41.3)
|
0.85 (0.57; 1.28)
|
0.43
|
1.04 (0.70; 1.54)
|
0.86
|
- AGA appropriate for gestational age, SGA small for gestational age
- aAcute: only parasites and minimal hemozoin deposition in the macrophages but not fibrin; Chronic: parasites and Hemozoin deposition; Past: hemozoin usually mixed with fibrin but no parasites. Severity of acute chorioamnionitis and funiculitis (acute histologic chorioamnionitis) was graded histologically as early (grade 1), intermediate (grade 2) and advanced (grade 3) following the Redline-classification [17, 18]
- bAdjusted for birth month
