The current distribution and characterization of the L1014F resistance allele of the kdr gene in three malaria vectors (Anopheles gambiae, Anopheles coluzzii, Anopheles arabiensis) in Benin (West Africa)

Table 2 Distribution frequency of the L1014F resistant allele of the Kdr gene F (L1014F) in the An.Coluzzii and An.Gambiae species

Agro-ecological zones	N_T	N	An. gambiae				An. coluzzii				P-value
			N₁ 1014F/	N₂ 1014F/	N₃ 1014L/	F(L1014F)%	N₁ 1014F/	N₂ 1014F/	N₃ 1014L/	F(L1014F)%
			1014F	1014L	1014L	F(L1014F)%	1014F	1014L	1014L	F(L1014F)%
Far north zone	30	0	0	0	0	0	21	6	3	80 ± 10.12	-
Northern cotton zone	30	29	23	3	3	84.48 ± 9.32	1	0	0	100	1
South-Borgou food crop production zone	60	58	50	6	2	91.38 ± 5.11	2	0	0	100	1
Western Atacora zone	31	27	25	2	0	96.30 ± 5.04	3	1	0	87.5 ± 22.92	0.842
Central cotton zone	150	62	54	8	0	93.55 ± 4.32	65	12	6	85.54 ± 5.35	0.0496
Bar land zone	192	75	74	1	0	99.33 ± 1.30	89	22	3	87.72 ± 4.26	< 0.001
Fishery zone	184	8	8	0	0	100	140	31	4	88.86 ± 3.30	0.3181
Total	677	259	234	20	5	94.21 ± 2.01	321	72	16	87.29 ± 2.28	< 0.001

F (L1014F)%: frequency of the L1014F allele of the Kdr gene of the different species; NT: cumulative total number of species by agro - ecological zone; N: represents the number of each species; N1: number of homozygous resistant genotype 1014F/1014F; N2: the heterozygous genotype 1014F/1014L; N3: number of susceptible homozygous genotype 1014L/1014L; 1014F/1014F: resistant homozygous genotype; 1014F/1014L: heterozygous genotype; 1014L/1014L: susceptible homozygous genotype

ISSN: 1475-2875