Table 2 Demographic and clinical characteristics of the follow-up subcohort at presentation compared to the original cohort (p values were calculated using either t tests for continuous variables or Fisher’s exact test for dichotomous variables)
Parameter | Units | Original cohort | Follow up subcohort | p value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
N | % | Mean | SD | N | % | Mean | SD | |||
Age | Years | 90 | – | 4.2 | 2.4 | 31 | – | 4.6 | 2.4 | 0.99 |
Pulse | /min | 94 | – | 124.1 | 21.8 | 31 | – | 115.2 | 27.513 | 0.84 |
Temperature | °C | 94 | – | 38.3 | 1.2 | 31 | – | 38.2 | 2.17 | 1.00 |
Respiratory rate | /min | 94 | – | 36.1 | 10.9 | 31 | – | 32.7 | 10.86 | 0.94 |
Haemoglobin | g/dL | 94 | – | 8.9 | 2.3 | 30 | – | 18.25 | 49.09 | 0.83 |
Platelets | 1000/µL | 94 | – | 101.6 | 87.3 | 30 | – | 95.93 | 58.87 | 0.90 |
White blood cells | 1000/µL | 94 | – | 9.3 | 6.2 | 30 | – | 9.53 | 5.99 | 1.00 |
Glucose | mmol/L | 78 | – | 4.8 | 1.7 | 21 | – | 5.5 | 2.74 | 0.99 |
Creatinine | g/L | 75 | – | 35.1 | 64.5 | 24 | – | 22.46 | 8.541 | 0.80 |
Bilirubin | g/L | 78 | – | 132.0 | 827.5 | 23 | – | 33 | 36.9 | 0.05 |
ALT | U/L | 78 | – | 35.7 | 36.3 | 24 | – | 32.3 | 39.95 | 0.94 |
Haemoglobinuria | % included patients | 93 | 2.2 | – | – | 30 | 0 | – | – | 1 |
Respiratory distress | % included patients | 93 | 6.4 | – | – | 30 | 0 | – | – | 0.33 |
Deep breathing | % included patients | 94 | 2.1 | – | – | 31 | 0 | – | – | 1 |
Severe vomiting | % included patients | 93 | 2.2 | – | – | 30 | 0 | – | – | 1 |
Prostration | % included patients | 93 | 20.4 | – | – | 30 | 3.2 | – | – | 0.1 |
Coma | % included patients | 93 | 4.3 | – | – | 30 | 0 | – | – | 0.57 |
Repeated generalized seizures | % included patients | 93 | 7.5 | – | – | 30 | 3.3 | – | – | 0.68 |
Jaundice | % included patients | 93 | 4.3 | – | – | 30 | 0 | – | – | 0.57 |
Severe anaemia | % included patients | 93 | 8.6 | – | – | 30 | 0 | – | – | 0.20 |
Hypoglycaemia | % included patients | 93 | 3.2 | – | – | 30 | 3.3 | – | – | 1 |
Cerebral malaria | % included patients | 93 | 6.4 | – | – | 31 | 3.3 | – | – | 0.68 |