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Table 1 Patient characteristics at baseline and randomization

From: Safety and tolerability of single low-dose primaquine in a low-intensity transmission area in South Africa: an open-label, randomized controlled trial

 

Total RDT positives screened [n = 181]

Randomized to primaquine [n = 70]

Not randomized to primaquine [n = 70]

Age (years)

32.1 (24.8–38.7)

32.2 (24.8–39.6)

32.4 (24.3–38.8)

Gender, female n (%)

55 (30.4)

22 (31.4)

16 (22.9)

Bodyweight (kg)

60 (55–64)

60 (53–63)

60 (55–64)

Day 0 haemoglobin (g/dL)

12.9 (11.3–14.2)

13.0 (11.6–14.5)

13.3 (11.6–14.5)

Day 0 anaemia (< 10 g/dL)

14/177 (7.9)

4/70 (5.7)

3/69 (4.4)

Day 3 haemoglobin (g/dL)

12.5 (11.2–13.7)

12.4 (11.3–13.9)

13.0 (11.7–13.6)

Day 3 anaemia (< 10 g/dL)

18/150 (12.0)

5/70 (7.1)

7/70 (10)

Day 0 asexual parasite density/per µL, geometric mean (95% CI)

5554 (3971–7768)

5048 (2933–8688)

4769 (2782–8175)

Day 0 multiplicity of infection (2 or more clones detected)

121/165 (73.3)

41/65 (63.1)

50/63 (79.4)

Day 0 gametocyte prevalence by microscopy

5 (2.3)

3 (4.3)

2 (2.9)

Day 0 gametocyte prevalence by PCR

109/176 (61.9)

48/69 (57.8)

35/68 (42.2)

  1. Categorical variables summarized as number (%); continuous variables summarized as median (IQR), unless otherwise stated