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Fig. 1 | Malaria Journal

Fig. 1

From: In vitro and in vivo characterization of anti-malarial acylphenoxazine derivatives prepared from basic blue 3

Fig. 1

Synthesis and structure of ITT derivatives. a Structure of basic blue 3 (i) and ITT derivatives (ITT-001 to 006) (ii). (i) The “10” indicates the nitrogen atom at the 10-position of the phenoxazine ring, which was modified to acyl group as shown in (ii). (ii) “R” indicates alkyl group replaced with an acyl group as shown in lower panel. b Visual confirmation of colour of basic blue 3 and ITT-001 to 006. The compounds were visualized at 1 mM in dimethyl sulfoxide (DMSO)

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