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Fig. 4 | Malaria Journal

Fig. 4

From: Absence of kelch13 artemisinin resistance markers but strong selection for lumefantrine-tolerance molecular markers following 18 years of artemisinin-based combination therapy use in Mpumalanga Province, South Africa (2001–2018)

Fig. 4

a Prevalence of the mdr86Y and crt76T mutations in Plasmodium falciparum isolates from Ehlanzeni District, Mpumalanga Province, South Africa, by year (2001–2018). Mutations at both codons were assessed in 2001, 2011 and 2018, with mutations in the mdr1 gene also assessed in 2009, b changes in the prevalence of pure wild-type mdr86N, pure mutant mdr86Yand mixed mdrN86Y alleles (2001–2018) and c prevalence of pure wild-type crt76K, pure mutant crt76T and mixed crtK76T alleles (2001–2018)

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Malaria Journal

ISSN: 1475-2875

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