Quantitative structure–activity relationship to predict the anti-malarial activity in a set of new imidazolopiperazines based on artificial neural networks

Table 4 The pair correlation coefficient (R²) and the variance inflation factor (VIF) for the 6 descriptors at the training and total set for W2 model

	Mor20p	MATS7m	RDF020m	MLOGP	BEHm3	Mor23u	VIF
Mor20p
Training set	1.00						1.63
Total set^a	1.00						2.67
MATS7m
Training set	0.00	1.00					1.62
Total set^a	0.00	1.00					1.64
RDF020m
Training	0.02	0.01	1.00				1.56
Total set^a	0.011	0.00	1.00				1.41
MLOGP
Training set	0.15	0.18	0.07	1.00			1.91
Total set^a	0.04	0.20	0.01	1.00			1.55
BEHm3
Training set	0.01	0.08	0.19	0.00	1.00		1.34
Total set^a	0.38	0.00	0.01	0.14	1.00		2.24
Mor23u
Training set	0.14	0.13	0.00	0.00	0.01	1.00	1.38
Total set^a	0.39	0.19	0.07	0.00	0.15	1.00	2.21

ISSN: 1475-2875