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Table 5 Impact of IPTp on the risk of malaria in infancy

From: Impact of Plasmodium falciparum malaria and intermittent preventive treatment of malaria in pregnancy on the risk of malaria in infants: a systematic review

Author, year of publication Randomized
Y/N
IPTp arm (n) Measure of association (95% CI), p-value Confounders adjusted for
Ruperez,, 2016 [38] Yes IPTp-SP (1432) Reference Country
IPTP-MQ (2815) IRR = 0.95 (0.81–1.13), p = 0.60
Awine, 2016 [19] Yes IPTp-SP (495) Reference Gender, social economic status, residence, irrigated area, season, ITN use, baseline parasitaemia, maternal haemoglobin
ISTp-AL (493) IRR = 0.94 (0.68–1.59), p = 0.76
Asante, 2013 [20] No IPTp-SP (1755) Reference Unadjusted
No IPTp (97) HR = 1.23 (0.93–1.59), p = 0.15
Bardaji, 2011 [16] Yes Placebo (500) Reference Unadjusted
IPTp-SP (497) OR = 1.28 (0.90–1.83), p = 0.17
  1. AL artemether lumefantrine, CI confidence interval, IPTp intermittent preventive treatment of malaria in pregnancy, IRR incident rate ratio, ISTp intermittent screening and treatment of malaria in pregnancy, ITN insecticide treated nets, HR hazard ratio, MQ mefloquine, SP sulfadoxine–pyrimethamine