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Table 2 Data of interest extracted from the included studies

From: A systematic review on anti-malarial drug discovery and antiplasmodial potential of green synthesis mediated metal nanoparticles: overview, challenges and future perspectives

Information groups Data retrieved
Group 1: General information Name of the first author
The year of publication
Characteristics of living organism used for synthesis of metal NPs (scientific name, common name, family, morphological type, type of microorganism and origin of isolation
Group 2: Data on mode of synthesis of NPs Biological material
Quantity of biological material
Metal source
Extraction solvent
Group 3: Methods used for physical characterization of metal NPs Shape
Size
Size distribution
Silver content
Stability
Structure-crystallinity
Group 4: Data on method used for evaluation antiplasmodial activity of NPs Study design (in vivo, in vitro)
Nature and origin of Plasmodium strain
Negative and positive controls
NPs doses tested
Group 5: Data on physical properties of NPs Size, shape, color
Maximum absorption peak
Aggregation phenomenon
Group 6: Data on antiplasmodial efficacy of NPs and their cytotoxic activity 50% inhibitory concentration (IC50) and/or percentage parasite growth inhibition
Tests used to appraise the NPs toxicity
Side effects recorded