Table 2 Data of interest extracted from the included studies
Information groups | Data retrieved |
|---|---|
Group 1: General information | Name of the first author |
The year of publication | |
Characteristics of living organism used for synthesis of metal NPs (scientific name, common name, family, morphological type, type of microorganism and origin of isolation | |
Group 2: Data on mode of synthesis of NPs | Biological material |
Quantity of biological material | |
Metal source | |
Extraction solvent | |
Group 3: Methods used for physical characterization of metal NPs | Shape |
Size | |
Size distribution | |
Silver content | |
Stability | |
Structure-crystallinity | |
Group 4: Data on method used for evaluation antiplasmodial activity of NPs | Study design (in vivo, in vitro) |
Nature and origin of Plasmodium strain | |
Negative and positive controls | |
NPs doses tested | |
Group 5: Data on physical properties of NPs | Size, shape, color |
Maximum absorption peak | |
Aggregation phenomenon | |
Group 6: Data on antiplasmodial efficacy of NPs and their cytotoxic activity | 50% inhibitory concentration (IC50) and/or percentage parasite growth inhibition |
Tests used to appraise the NPs toxicity | |
Side effects recorded |